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Network
- inetnum : 99.83.64.0 - 99.84.255.255
- name : AMAZO-4
- handle : NET-99-83-64-0-1
- status : Direct Allocation
- created : 2005-09-29
- changed : 2022-09-30
- desc : For details of this service please see,http://ec2.amazonaws.com
Owner
- organization : Amazon.com, Inc.
- handle : AMAZO-4
- address : Array,Seattle,WA,98108-1226,US
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| Location | Seattle United States |
| Latitude | 47.54 |
| Longitude | -122.3032 |
| Metro Code | 819 |
| Timezone | America/Los_Angeles |
| Postal | 98108 |
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Alprolix - FDA prescribing information, side effects and uses
Alprolix is a recombinant, fusion protein that temporarily replaces the missing coagulation Factor IX needed for effective hemostasis. Alprolix contains the Fc region of human IgG 1, which binds to the neonatal Fc receptor (FcRn). FcRn is part of a naturally occurring pathway that delays lysosomal degradation of immunoglobulins by cycling them ...
Drugs.comDA: 13 PA: 18 MOZ Rank: 31
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS
ALPROLIX has no influence on the ability to drive and use machines. 4.8 Undesirable effects . Summary of the safety profile Hypersensitivity or allergic reactions (which may include angioedema, burning and stinging at the infusion site, chills, flushing, generalised urticaria, headache, hives, hypotension, lethargy, nausea, restlessness, tachycardia, tightness of the …
Ema.europa.euDA: 17 PA: 50 MOZ Rank: 92
ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein]
COPAY PROGRAM *†. Whether you're new to ALPROLIX or already on therapy, the copay program can cover up to $20,000 of your eligible out-of-pocket co-payment or co-insurance costs for ALPROLIX per year. Best of all, there are no income requirements or caps, so you can get started with your treatment the right way.
Alprolix.comDA: 16 PA: 31 MOZ Rank: 49
ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein]
How ALPROLIX mimics naturally occurring Factor IX. ALPROLIX is an EXTENDED HALF-LIFE Factor IX product that mimics how naturally occurring Factor IX works. It is designed with Fc Fusion which allows ALPROLIX to remain in the body for an extended period of time. Additionally, it has a high volume of distribution meaning it moves out of the ...
Alprolix.comDA: 16 PA: 33 MOZ Rank: 52
Alprolix® (rFIXFc) approved in the EU for the treatment of …
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with fewer prophylactic injections. Alprolix is indicated for both on-demand and prophylaxis treatment of people with haemophilia B in all ages. Prophylactically, it can be administered ...
Hospitalpharmacyeurope.comDA: 26 PA: 50 MOZ Rank: 46
European Union approves Alprolix (rFIXFc) for the Treatment of ...
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with fewer prophylactic injections. Alprolix is indicated for both on-demand and prophylaxis treatment of people with haemophilia B in all ages. Prophylactically, it can be administered ...
Pharmaadvancement.comDA: 25 PA: 50 MOZ Rank: 45
ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein]
ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider or seek emergency care if you have symptoms of a possible abnormal blood clot, which may include: chest pain, difficulty breathing, unexpected swelling of an arm or leg with or without pain or tenderness. …
Alprolix.comDA: 16 PA: 27 MOZ Rank: 49
ALPROLIX | FDA
October 19, 2017 Summary Basis for Regulatory Action - ALPROLIX; November 3, 2017 Approval Letter - ALPROLIX; Approval History, Letters, Reviews, and Related Documents - ALPROLIX; Supporting ...
Fda.govDA: 11 PA: 50 MOZ Rank: 76
Alprolix® (rFIXFc) Approved in the EU for the Treatment of
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with fewer prophylactic injections. Alprolix is indicated for both on-demand and prophylaxis treatment of people with haemophilia B in all ages. Prophylactically, it can be administered ...
Investors.biogen.comDA: 20 PA: 50 MOZ Rank: 42
Sanofi
Sanofi
Products.sanofi.caDA: 18 PA: 16 MOZ Rank: 43
Alprolix® (rFIXFc) Approved in the EU for the Treatment of …
Alprolix® (rFIXFc) Approved in the EU for the Treatment of Haemophilia B; First Fc Fusion Therapy Approved for haemophilia B in the EU to Provide Exte
Businesswire.comDA: 20 PA: 50 MOZ Rank: 40
Alprolix® (rFIXFc) Approved in the EU for the Treatment of …
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with fewer prophylactic injections. Alprolix is indicated for both on-demand and prophylaxis treatment of people with haemophilia B in all ages. Prophylactically, it can be administered ...
Biogen.gcs-web.comDA: 18 PA: 50 MOZ Rank: 39
ALPROLIX 250 IU powder and solvent for solution for injection
ALPROLIX (eftrenonacog alfa) is a long-acting, fully recombinant, fusion protein comprising human coagulation factor IX covalently linked to the Fc domain of human immunoglobulin G1, and produced by recombinant DNA technology. The Fc region of human immunoglobulin G1 binds with the neonatal Fc receptor. This receptor is expressed throughout …
Medicines.org.ukDA: 20 PA: 22 MOZ Rank: 54
Sobi's Alprolix approved in the EU
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with fewer prophylactic injections. Alprolix is indicated for both on-demand and prophylaxis treatment of people with haemophilia B in all ages. Prophylactically, it can be administered ...
Nordiclifescience.orgDA: 21 PA: 28 MOZ Rank: 62
DosingOnDemand - ALPROLIX® Pro
Minor and moderatea. 30-60. Repeat every 48 hours if there is further evidence of bleeding. Majorb. 80-100. Consider a repeat dose after 6-10 hours and then every 24 hours for the first 3 days. Due to the long half-life of ALPROLIX, the dose may be reduced and the frequency of dosing may be extended after Day 3 to every 48 hours or longer until ...
Alprolixpro.comDA: 19 PA: 18 MOZ Rank: 51
Resources - ALPROLIX® Pro
The treating physician is solely responsible for diagnosis, coding and determination of the appropriate ICD-10-CM codes that describe the patient's condition and are supported by the medical record. The ICD-10-CM and HCPCS codes provided are based on AMA or CMS guidelines. Use of the information below does not guarantee that the payor will ...
Alprolixpro.comDA: 19 PA: 11 MOZ Rank: 45
Alprolix® (rFIXFc) approved in the EU for the treatment of
Alprolix is the only recombinant factor IX Fc Fusion protein therapy for haemophilia B to offer people in the EU prolonged protection against bleeding episodes with …
Globenewswire.comDA: 21 PA: 50 MOZ Rank: 34
ALPROLIX - saskatoonhealthregion.ca
ALPROLIX ® (Coagulation Factor IX (Recombinant), Fc Fusion Protein) is formulated as a sterile, non-pyrogenic, preservative free, and white to off-white, lyophilized powder to cake for intravenous administration in a single use vial; ALPROLIX ® is coagulation Factor IX made in the laboratory using recombinant technology. Availability
Saskatoonhealthregion.caDA: 28 PA: 50 MOZ Rank: 33
Biogen : Alprolix® (rFIXFc) Approved in the EU for the Treatment …
First Fc Fusion Therapy Approved for haemophilia B in the EU to Provide Extended Protection Against Bleeds ... | November 22, 2021
Marketscreener.comDA: 22 PA: 50 MOZ Rank: 32
Alprolix® (rFIXFc) approved in the EU for the treatment of …
First Fc Fusion therapy approved for haemophilia B in the EU to provide extended protection against bleeds
Sobi.comDA: 12 PA: 50 MOZ Rank: 31
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