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码头电影网-2024最新电影电视剧

码头电影网提供最新最快的影视资讯和在线播放！无广告免费看视频！码头电影网app是一款可以观看海量短视频资源的软件，码头电影网涵盖的类型是非常丰富的，还会根据大家 …

Zgvmj.com

DA: 13 PA: 13 MOZ Rank: 14

ULK1 - Wikipedia

ULK1 is an enzyme that in humans is encoded by the ULK1 gene. Unc-51-like autophagy-activating kinases 1 and 2 (ULK1/2) are two similar isoforms of an enzyme that in humans is encoded by the ULK1/2 genes. The enzyme is specifically a kinase that is involved with autophagy, particularly in response to amino acid withdrawal. Not many studies have been done compa…

En.wikipedia.org

DA: 16 PA: 10 MOZ Rank: 27

ULK1 promotes mitophagy via phosphorylation and stabilization …

Oct 15, 2021 UNC51-like kinase-1 (ULK1) is the catalytic component of the autophagy pre-initiation complex that stimulates autophagy via phosphorylation of ATG14, BECLN1 and …

Nature.com

DA: 14 PA: 28 MOZ Rank: 44

AMPK and mTOR regulate autophagy through direct ... - Nature

Jan 23, 2011 Article Open access 20 October 2020. Main. Under nutrient starvation, cells initiate a lysosomal-dependent self-digestive process known as autophagy, whereby …

Nature.com

DA: 14 PA: 17 MOZ Rank: 34

ULK1 inhibition overcomes compromised antigen presentation …

May 17, 2021 Wong and colleagues show that LKB1-deficient lung tumors are sensitive to autophagy inhibition, which can restore impaired antigen presentation and antitumor …

Nature.com

DA: 14 PA: 28 MOZ Rank: 46

The mammalian ULK1 complex and autophagy initiation - PubMed

Dec 12, 2017 This step is mediated by the serine/threonine protein kinase ULK1 (unc-51-like kinase 1), which functions in a complex with at least three protein partners: FIP200 …

Pubmed.ncbi.nlm.nih.gov

DA: 23 PA: 10 MOZ Rank: 38

ULK1 unc-51 like autophagy activating kinase 1 [ (human)]

ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation. Transferrin promotes chondrogenic differentiation in condylar growth through inducing …

Ncbi.nlm.nih.gov

DA: 20 PA: 10 MOZ Rank: 36

Autophagy and beyond: Unraveling the complexity of UNC

Oct 1, 2022 UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in …

Sciencedirect.com

DA: 21 PA: 38 MOZ Rank: 66

Metformin Mitigates Adipogenesis of Fibro-adipogenic …

1 day ago ABSTRACT Muscular fatty infiltration is a common issue after rotator cuff tears (RCT) which impairs shoulder function. Females suffer higher prevalence and more …

Journals.physiology.org

DA: 23 PA: 36 MOZ Rank: 67

ULK1 induces autophagy by phosphorylating Beclin-1 and

May 19, 2013 1083 Citations. 13 Altmetric. Metrics. Abstract. Autophagy is the primary cellular catabolic program activated in response to nutrient starvation. Initiation of …

Nature.com

DA: 14 PA: 17 MOZ Rank: 40

Frontiers | ULK1 Signaling in the Liver: Autophagy Dependent and ...

Feb 18, 2022 The uncoordinated-51-like kinases 1 (ULK1) is a proximal kinase member of the Atg family that plays a crucial role in autophagy. Interestingly, ULK1 actions on …

Frontiersin.org

DA: 19 PA: 40 MOZ Rank: 69

UNC-51-like Kinase 1: From an Autophagic Initiator to ... - PubMed

Aug 9, 2018 UNC-51-like kinase 1 (ULK1), known as an ortholog of the yeast Atg1, is the serine-threonine kinase and the autophagic initiator in mammals. Accumulating …

Pubmed.ncbi.nlm.nih.gov

DA: 23 PA: 10 MOZ Rank: 44

ULK1 and ULK2 are less redundant than previously thought

Jul 2, 2020 Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting homeostasis and intracellular defence. …

Nature.com

DA: 14 PA: 28 MOZ Rank: 54

The ULK1 complex - PMC - National Center for Biotechnology …

Feb 1, 2013 The Atg1/ULK1 complex plays a central role in starvation-induced autophagy, integrating signals from upstream sensors such as MTOR and AMPK and transducing …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 58

Phosphorylation of ULK1 affects autophagosome fusion and links …

Aug 28, 2018 ULK1 is a serine/threonine-specific protein kinase. The ULK1 complex is made of autophagy-related protein 13 (ATG13), which contains the HORMA domain, the …

Nature.com

DA: 14 PA: 28 MOZ Rank: 56

Structure and Function of the ULK1 Complex in Autophagy

The ULK1 complex initiates autophagosome formation, linking cellular nutrient status to downstream events in autophagy. Recent work suggests that the ULK1 complex might …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 60

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