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- inetnum : 45.60.0.0 - 45.60.255.255
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- created : 2010-09-15
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Reblozyl® (luspatercept-aamt) for anemia in MDS …
REBLOZYL caused increased post-implantation loss, decreased litter size, and an increased incidence of skeletal variations in pregnant rat and rabbit studies. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment and for at least 3 months after the final dose.
Reblozylpro.comDA: 19 PA: 19 MOZ Rank: 20
Reblozyl® (luspatercept-aamt) Access & Reimbursement
The following distributors are authorized to sell REBLOZYL and are able to service qualified accounts. Authorized distributor network. Community practices. Phone. Fax. Cardinal Specialty. 1-877-453-3972. McKesson Specialty Health. 1-800-482-6700.
Reblozylpro.comDA: 19 PA: 16 MOZ Rank: 36
Reconstitution - www.reblozylpro.com
Important considerations for REBLOZYL reconstitution 1. Reconstitute the number of REBLOZYL vials to achieve the appropriate dose based on the patient’s weight. Use a syringe with suitable graduations for reconstitution to ensure accurate dosage. Adhere to the following steps to properly reconstitute REBLOZYL 1.
Reblozylpro.comDA: 19 PA: 16 MOZ Rank: 37
REBLOZYL Product Monograph Page 1 of 38 - Bristol Myers Squibb
Reblozyl® should be reconstituted and administered by a healthcare professional. Reconstitute Reblozyl® with Sterile Water for Injection, USP only. Table 3 - Reconstitution Volumes Vial Size Amount of Sterile Water for Injection, USP required for reconstitution Approximate Available Volume Nominal Concentration per mL ® ®
Bms.comDA: 11 PA: 50 MOZ Rank: 74
Mechanism of Action in MDS | Reblozyl (luspatercept)
Reblozyl®is a recombinant fusion protein that binds selected TGF-β superfamily ligands to reduce Smad 2/3 signaling, which is abnormally high in disease models characterized by ineffective erythropoiesis, (ie, MDS and β-thalassemia).1-3 Reblozyl®is the first and only erythroid maturation agent1
Reblozyl.beDA: 11 PA: 25 MOZ Rank: 40
Reblozyl BEAM-BMS CST
REBLOZYL may cause fetal harm when administered to a pregnant woman. REBLOZYL caused increased post-implantation loss, decreased litter size, and an increased incidence of skeletal variations in pregnant rat and rabbit studies. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment …
Beambms-reblozyl.herokuapp.comDA: 30 PA: 30 MOZ Rank: 36
β-Thalassemia Patient Eligibility for Reblozyl (luspatercept)
The potential benefit of treatment with Reblozyl ® in β-thalassemia should be weighed against the potential risk of TEEs in patients with a splenectomy and other risk factors for developing TEE. Thromboprophylaxis according to current clinical guidelines should be considered in patients with β-thalassemia at higher risk .
Reblozyl.beDA: 11 PA: 25 MOZ Rank: 42
Reblozyl® (luspatercept-aamt) l MDS-RS l Dosing Information l HCP
Dose modifications for predose Hgb levels or rapid Hgb rise. Predose Hgb is ≥ 11.5 g/dL in the absence of transfusions. Interrupt treatment. Restart when the Hgb is no more than 11 g/dL. Increase in Hgb > 2 g/dL within 3 weeks in the absence of transfusions and. current dose is 1.75 mg/kg. current dose is 1.33 mg/kg.
Reblozylpro.comDA: 19 PA: 27 MOZ Rank: 53
REBLOZYL (luspatercept-aamt) label
REBLOZYL is a colorless to slightly yellow, clear to slightly opalescent solution which . 4 . is free of foreign particulate matter. Do not use if undissolved product or foreign particulate matter are observed. 8. If the reconstituted solution is not used immediately: • Store at room temperature at 20°C to 25°C (68°F to 77°F) in the original vial for up to 8 hours. Discard if not used ...
Accessdata.fda.govDA: 22 PA: 41 MOZ Rank: 71
Reblozyl (Luspatercept-aamt for Injection ): Uses, Dosage ... - RxList
The recommended starting dose of REBLOZYL is 1 mg/kg once every 3 weeks by subcutaneous injection for patients with anemia of MDS-RS or MDS/MPN-RS-T. Prior to each REBLOZYL dose, review the patient’s hemoglobin and transfusion record. Titrate the dose based on responses according to Table 3. Interrupt treatment for adverse reactions as described in …
Rxlist.comDA: 14 PA: 18 MOZ Rank: 41
Reblozyl (luspatercept) dosing, indications, interactions, adverse ...
Predose hemoglobin ≥11.5 g/dL in absence of transfusions: Interrupt dose; restart when Hgb ≤11 g/dL. Increase in hemoglobin >2 g/dL within 3 weeks in absence of transfusions AND. Current dose is 1.75 mg/kg: Reduce to 1.33 mg/kg. Current dose is 1.33 mg/kg: Reduce to 1 mg/kg. Current dose is 1 mg/kg: Reduce to 0.8 mg/kg.
Reference.medscape.comDA: 22 PA: 35 MOZ Rank: 67
Including patient medication information - CARE™ Education
Reblozyl should be reconstituted and administered by a healthcare professional. Calculate the exact total dosing volume of 50 mg/mL solution required for the patient as per Table 3. Slowly withdraw the dosing volume of the reconstituted Reblozyl solution from the single-dose vial(s) into a syringe. Divide doses requiring larger reconstituted volumes (i.e., greater than 1.2 mL) into …
Careeducation.caDA: 16 PA: 50 MOZ Rank: 85
Reblozyl® (Luspatercept-Aamt) – Individual Exchange Medical …
No transfusion-free period greater than 35 days during that period were randomized 2:1 to Reblozyl (n=224) or placebo (n=112). In BELIEVE, Reblozyl was administered subcutaneously once every three weeks as long as a reduction in transfusion requirement was observed or until unacceptable toxicity. All patients were eligible to receive best ...
Uhcprovider.comDA: 19 PA: 50 MOZ Rank: 99
REBLOZYL DOSING AND RECONSTITUTION GUIDE
REBLOZYL is administered subcutaneously and is available in 2 vial sizes (25 mg and 75 mg) 1 • Prior to injection, allow solution to reach room temperature for a more comfortable injection Front Back NOTE: Discard any unused portion. Do not pool unused portions from the vials. Do not administer more than 1 dose from a vial. • Do not mix with other medications • If multiple …
Media.reblozylpro.comDA: 21 PA: 50 MOZ Rank: 37
Acceleron Announces Third Quarter 2021 REBLOZYL ® Net Sales
Acceleron expects to report royalty revenue of approximately $32.0 million from net sales of REBLOZYL in the third quarter ended September 30, 2021. This compares with approximately $25.6 million ...
Businesswire.comDA: 20 PA: 50 MOZ Rank: 36
Reblozyl® (Luspatercept-Aamt) – Commercial Medical Benefit …
O Reblozyl is prescribed by, or in consultation with, a hematologist, oncologist, or other specialist with expertise in the diagnosis and management of myelodysplastic syndromes; and o Reblozyl dosing is in accordance with the FDA approved labeling; and o Initial authorization will be for no more than 3 months. Continuation of Therapy
Uhcprovider.comDA: 19 PA: 50 MOZ Rank: 35
How to pronounce Reblozyl | HowToPronounce.com
How to say Reblozyl in English? Pronunciation of Reblozyl with 1 audio pronunciation, 1 meaning and more for Reblozyl.
Howtopronounce.comDA: 22 PA: 9 MOZ Rank: 47
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