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Polysialic acid

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Polysialic acid - Wikipedia

Polysialic acid (polySia) is polymer of linearly repeating monomer units of α2,8- and α2,9-glycosidic linked sialic acid residues. Sialic acid refers to carboxylated 9-carbon sugars, 2-keto-3-dexoxy-D-glycero-nononic acids. An unusual property of this sugar is that it often polymerizes into polySia. This is accomplished by attaching the monomers to the nonreducing end of the glycan. This mostly consists of Neu5Ac subunits. It is polyanionic and bulky, meaning there is little abilit…

En.wikipedia.org

DA: 16 PA: 21 MOZ Rank: 37

Polynesia - Wikipedia

Polynesia (UK: / ˌ p ɒ l ɪ ˈ n iː z i ə /, US: /-ˈ n iː ʒ ə /) is a subregion of Oceania, made up of more than 1,000 islands scattered over the central and southern Pacific Ocean.The indigenous people who inhabit the islands of Polynesia are called Polynesians.They have many things in common, including language relatedness, cultural practices, and traditional beliefs.

En.wikipedia.org

DA: 16 PA: 15 MOZ Rank: 32

Polyscias Information & tips - Plant Guide - FloraStore

Watering. It is important that the Polyscias retain a moist soil in summer. It is therefore advisable to water regularly. It is easy to check whether the soil is still moist by simply putting a finger into the soil. Make sure that the plant is not constantly under water. The …

Florastore.com

DA: 18 PA: 26 MOZ Rank: 46

Polyuria: Symptoms, Causes, Diagnosis, Treatment

Type 1 and type 2 diabetes . Polyuria is often one of the first signs of diabetes. The condition makes sugar build up in your bloodstream. If your kidneys aren’t able to filter it out, it exits ...

Webmd.com

DA: 13 PA: 33 MOZ Rank: 49

Ming Aralia: Indoor Plant Care & Growing Guide - The Spruce

Its ferny, feathery leaves droop from graceful narrow branches that grow straight up, forming a many-layered, complex plant. Ming aralia grows slowly just like false aralia but can eventually reach over 6 feet in height with the proper care. While it can be considered an outdoor ornamental shrub in USDA hardiness zones 11 and 12, it's most commonly cared for indoors, …

Thespruce.com

DA: 17 PA: 33 MOZ Rank: 54

Low molecular weight polysialic acid binds to properdin and …

PolySia avDP20, biotin-conjugated polySia avDP20, high molecular weight polysialic acid, monosialic acid, oligosialic acid DP3 and DP5, low and high-sulfated dextran, and chondroitin sulfate

Nature.com

DA: 14 PA: 28 MOZ Rank: 47

Polysialic Acid - an overview | ScienceDirect Topics

Polysialic acid (polySia) [1] is a developmentally regulated carbohydrate polymer involved in neural cell differentiation [2, 3], organogenesis [4] and malignancies [5–8]. It is a linear homopolymer of N-acetylneuraminic acid units joined by α2–8 linkages [9]. The main carrier of polySia in eukaryotes is the neural cell adhesion molecule (NCAM), whose adhesion …

Sciencedirect.com

DA: 21 PA: 36 MOZ Rank: 63

Direct binding of polysialic acid to a brain-derived neurotrophic ...

Whether polySia also functions as a positive regulator in the nervous system through binding to specific ligands is not known. In the present study, we demonstrated that a brain-derived neurotrophic factor (BDNF) dimer binds directly to polySia to form a large complex with an M(r) greater than 2000 kDa under physiologic conditions. Although somewhat affected by the …

Pubmed.ncbi.nlm.nih.gov

DA: 23 PA: 10 MOZ Rank: 40

Groups & Conventions | Polynesian Cultural Center

Availability: Monday–Saturday 7:00am–3:00pm or 3:00pm–11:00pm. Blackout dates apply. The PCC’s beautifully landscaped Hale Aloha or “House of Love” dinner theater — home of our award-winning Alii Luau — is our unforgettably spectacular Polynesian setting where groups of up to 650 people can enjoy meetings topped off by a ...

Polynesia.com

DA: 17 PA: 7 MOZ Rank: 32

Accelerated production of α2,8- and α2,9-linked polysialic acid in ...

The polySia produced was successfully isolated using a validated purification process. The yields for endogenous polySia from E. coli28,36]. 1 H-NMR spectroscopy confirmed that two of the recombinant strains produce α2,8-linked polySia. However, the exchange of neuS with synE in the kps gene cluster also enables the synthesis of α2,9-linked polySia in E. coli …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 54

What Is Polynesia? - WorldAtlas

A local man canoeing for food delivery in an island resort in French Polynesia, a part of Polynesia. Image credit: Shen max/Shutterstock.com. Polynesia is a group of over 1,000 islands in the Pacific Ocean that form a triangle with Hawaii in the north, Easter Island in the east, and New Zealand in the south.

Worldatlas.com

DA: 18 PA: 32 MOZ Rank: 60

Antibody-Mediated Endocytosis of Polysialic Acid Enables …

PolySia is a rare posttranslational modification that is found on a select group of identified carrier proteins including NCAM, SynCAM-1, Neuropilin-2, and the voltage-sensitive sodium channel α subunit . To create a more therapeutically relevant polySia-directed antibody, we engineered a chimerized human mAb, ch735, that was based on mouse-derived mo735, …

Aacrjournals.org

DA: 16 PA: 50 MOZ Rank: 39

Polydipsia: Causes, Symptoms, and Treatments - Healthline

having blurry vision. exhaustion. abnormal weight loss. getting frequent sores or infections. slow healing of sores or infections. Drinking …

Healthline.com

DA: 18 PA: 27 MOZ Rank: 57

Polysialic acid and Siglec-E orchestrate negative ... - SpringerLink

BV2 cells produce polySia on NRP2 and ESL-1. The murine microglial cell line BV2 is a commonly used model system and suited to study inflammatory microglia activation [].As shown before [], LPS-induced activation of these cells can be dose dependently inhibited by externally applied polySia.For the use of BV2 cells in the current study, we validated, if these …

Link.springer.com

DA: 17 PA: 35 MOZ Rank: 65

Polysialylation and disease - ScienceDirect

PolySia-positive transplanted cells promote neural tissue integrity and improve behavioral performance in a rat stroke model. 10. Application of polySia and polySia probes in medical fields. The first application of polySia or polySia-related molecules for a medical treatment was the production of vaccines for neuroinvasive bacteria, such as Neisseria …

Sciencedirect.com

DA: 21 PA: 38 MOZ Rank: 73

Taste Polynesia - A unique culinary experience - Polynesian …

Ground ovens are traditional throughout the Polynesian Islands. In the early morning hours at the Center a Hawaiian ground oven, or imu, is built and used to dry age and steam a whole roasted pig for 10 hours to ensure the most tender and delicious meat. This practice is common for luaus and has been passed down through the generations.

Polynesia.com

DA: 17 PA: 16 MOZ Rank: 48

Interaction of Polysialic Acid with CCL21 Regulates the ... - PLOS

Corresponding to polySia, the expression level of CCR7 is maximal two days after TLR4 triggering. In contrast, although TLR agonists other than LPS induce upregulation of CCR7, they achieve only a moderate polySia expression. In situ we could detect polySia-expressing APCs in the T cell zone of the lymph node and in the deep dermis. Together ...

Journals.plos.org

DA: 17 PA: 16 MOZ Rank: 49

Unscramble POLYSIA - Unscrambled 154 words from letters in …

Unscramble POLYSIA POLYSIA unscrambles and makes 154 words!. Advanced Options . Starts With

Wordunscrambler.net

DA: 23 PA: 23 MOZ Rank: 41

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