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Podocyte.org lookup results from http://rdap.routing.net server:
- Domain created: 2005-01-18T08:00:43Z
- Domain updated: 2024-03-03T08:01:11Z
- Domain expires: 2025-01-18T08:00:43Z 0 Years, 204 Days left
- Website age: 19 Years, 160 Days
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| Host name | fo2.cekom.com |
| IP address | 178.63.45.241 |
| Location | Germany |
| Latitude | 51.2993 |
| Longitude | 9.491 |
| Timezone | Europe/Berlin |
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Podocyte
The Clinical Research Unit (CRU) 329 "Disease pathways in podocyte injury – from molecular mechanisms to individualized treatment options" is an interdisciplinary, cross-faculty research center of excellence funded through …
Podocyte.orgDA: 16 PA: 16 MOZ Rank: 17
Podocyte - Wikipedia
Podocytes are cells in Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus. Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. Bowman's capsule filters the blood, retaining large molecules such as proteins while smaller molecules such as water, salts, and sugars are filtered as the first step in the formation of urine. Although various viscera have epithelial layers, the name visceral epithelial cell…
En.wikipedia.orgDA: 16 PA: 14 MOZ Rank: 31
Podocytes - PMC
If podocyte loss is less than this threshold, then podocytes have the capacity to recover the normal structure of a healthy glomerulus. Administration of lipopolysaccharides (LPS) is an example of such a reversible model 57– 59. LPS trigger podocyte FP effacement and transient proteinuria within 24 hours, which return to baseline after 3 days 58.
Ncbi.nlm.nih.govDA: 20 PA: 25 MOZ Rank: 47
Podocyte — Wikipédia
Les podocytes sont des cellules épithéliales différenciées et ramifiées composant le feuillet viscéral de la capsule de Bowman au niveau du glomérule rénal. Leurs ramifications, nommées pédicelles, s’entrelacent autour des capillaires glomérulaires en ne laissant découvert que de petites fentes de filtration. Elles reposent sur une membrane basale, formée par la fusion de leur lame basale avec celle de l’endothélium des capillaires.
Fr.wikipedia.orgDA: 16 PA: 14 MOZ Rank: 33
Podocyte biology and pathogenesis of kidney disease
Histological and genetic data strongly implicate one promising target: the podocyte. Podocytes are terminally differentiated cells of the kidney glomerulus that are essential for the integrity of the kidney filter. Their function is primarily based on their intricate structure, which includes foot processes. Loss of these actin-driven membrane extensions is tightly connected to the …
Pubmed.ncbi.nlm.nih.govDA: 23 PA: 10 MOZ Rank: 37
Receptor activator of NF-kappaB and podocytes: towards …
Podocyte injury or podocyte loss in the renal glomerulus has been proposed as the crucial mechanism in the development of glomerulosclerosis. However, the mechanism by which podocytes respond to injury is poorly understood. TNF and TNF receptor superfamilies are important in the pathogenesis of podocyte injury and apoptosis. The ligand of receptor …
Pubmed.ncbi.nlm.nih.govDA: 23 PA: 10 MOZ Rank: 38
PoDocyte - YouTube
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Youtube.comDA: 15 PA: 33 MOZ Rank: 54
The Updates of Podocyte Lipid Metabolism in Proteinuric Kidney …
Targeting podocyte lipid metabolism will pave the way to new therapeutic approaches in podocyte injury and proteinuric kidney disease. Lipids in Podocyte Biological Function Lipids are not only the key structural components of biological membranes but also potent signal transduction molecules, orchestrating intra- and extracellular signal transmission …
Ncbi.nlm.nih.govDA: 20 PA: 25 MOZ Rank: 52
Frontiers | Podocyte Endocytosis in Regulating the Glomerular ...
A thorough understanding of podocyte endocytosis may shed novel insights into its biological function in maintaining a functioning filter and offer potential targeted therapeutic strategies for proteinuric glomerular diseases. Endocytosis is a mechanism that internalizes and recycles plasma membrane components and transmembrane receptors via vesicle formation, …
Frontiersin.orgDA: 19 PA: 39 MOZ Rank: 66
Podocyte | definition of podocyte by Medical dictionary
Podocyte: [ pod´o-sīt ] an epithelial cell of the visceral layer of a renal glomerulus, having a number of footlike radiating processes (pedicles).
Medical-dictionary.thefreedictionary.comDA: 40 PA: 9 MOZ Rank: 58
cAMP Signaling Prevents Podocyte Apoptosis via Activation of …
Introduction. Most glomerular diseases share the common features of proteinuria and effacement of podocyte foot processes .Recent studies have shown that podocyte injury is involved in the development of podocytopenia and glomerulosclerosis .The first event initiating the process of glomerulosclerosis is podocyte loss , .The remnant podocytes fail to cover the …
Ncbi.nlm.nih.govDA: 20 PA: 25 MOZ Rank: 55
Ischemic Injury to Kidney Induces Glomerular Podocyte …
Podocyte cells were grown on coverslips and sub- jected to ATP depletion for 30 min or 2 h. The recovery followed a 2-h injury 2HrD 2HrR 2HrD 30R 2HrD 15R and was performed by replacing the medium with fresh growth medium and growing the cells for the indicated times. At each time point, the cells were 2HrD 30D 60D stained with Neph1 and ZO-1 antibodies to determine the …
Academia.eduDA: 16 PA: 50 MOZ Rank: 39
PEMP - NIPOKA
Quantification of podocyte foot process morphology. Request a Demo NIPOKA is supported by the European Union and the State of Mecklenburg-Western Pomerania P odocyte E xact Morphology M easurement P rocedure PEMP is a quantitative and quick procedure measuring the slit membrane density. It is ideal to determine the exact foot process morphology in biopsies …
Nipoka.comDA: 10 PA: 10 MOZ Rank: 23
Asparaginyl endopeptidase protects against podocyte injury in
Subsequently, podocyte injury, urinary albumin excretion, and the severity of glomerular injury were significantly aggravated in AEP knockout mice, suggesting that AEP protects against podocyte ...
Nature.comDA: 14 PA: 28 MOZ Rank: 55
Investigating the Molecular Mechanism of Quercetin Protecting …
Quercetin (QUE), a health supplement, can improve renal function in diabetic nephropathy (DN) rats by ameliorating podocyte injury. Its clinical trial for renal insufficiency in advanced diabetes ( NCT02848131 ) is currently underway. This study aimed to investigate the mechanism of QUE protecting against podocyte injury to attenuate DN through network …
Hindawi.comDA: 15 PA: 28 MOZ Rank: 57
MAD2B promotes podocyte injury through regulating Numb …
In addition, podocyte-specific MAD2B deletion in mice reversed the diabetes-induced decline of Nephrin (a podocyte marker protein) expression (Figure 3G) and loss of podocytes by observing WT 1-positive cells (Figure 3H-I). The above results suggest that increased MAD2B expression contribute to diabetic related podocyte injury which can be …
Ijbs.comDA: 12 PA: 13 MOZ Rank: 40
APOL1 risk variants affect podocyte lipid homeostasis and energy ...
GM3 is a glycosphingolipid that is highly enriched in lipid rafts on the podocyte surface where it interacts with receptors of vascular endothelial growth factor (VEGFR), thus promoting actin organization . A reduction of GM3 may cause reorganization of the podocyte actin cytoskeleton and foot process effacement. Taken together, the use of ...
Academic.oup.comDA: 16 PA: 31 MOZ Rank: 63
Mechanisms of podocyte injury and implications for diabetic …
Podocytes are highly specialised glomerular epithelial cells that form the GFB together with the fenestrated endothelium and the glomerular basement membrane (GBM) [1,2].The podocyte cell body bulges into the urinary space and gives rise to long primary processes that branch into foot processes (FPs), enwrapping the glomerular capillaries [].FPs …
Portlandpress.comDA: 17 PA: 50 MOZ Rank: 33
The podocyte's response to stress: the enigma of foot process ...
Profile of podocyte 2 does not show any connections to the GBM, although it appears to be connected to podocytes 1 and 3 by intercellular junctions (arrows). A very similar situation is seen in B with a completely detached podocyte profile (2) connected to 2 adjacent podocytes 1 and 3 by junctions (arrows); these latter cells are more closely attached to the …
Journals.physiology.orgDA: 23 PA: 37 MOZ Rank: 78
Blocking ribosomal protein S6 phosphorylation inhibits podocyte ...
Ribosomal protein S6 (rpS6) phosphorylation mediates the hypertrophic growth of kidney proximal tubule cells. However, the role of rpS6 phosphorylation in podocyte hypertrophy and podocyte loss during the pathogenesis of focal segmental glomerulosclerosis (FSGS) remains undefined. Here, we examined rpS6 phosphorylation levels in kidney biopsy …
Kidney-international.orgDA: 28 PA: 39 MOZ Rank: 86
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