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We found Websites Listing below when search with lncrna.caltech.edu on Search Engine

Contact | Guttman Lab at Caltech

Mailing Address: 1200 E. California Blvd. MC 140-18 Pasadena, CA 91125. Delivery Address: 391 S. Holliston Ave. Bio-73 Pasadena, CA 91106

Lncrna.caltech.edu

DA: 22 PA: 9 MOZ Rank: 31

www.lncrna.caltech.edu

Www.lncrna.caltech.edu

Lncrna.caltech.edu

DA: 22 PA: 10 MOZ Rank: 33

Guttman Lab at Caltech | lncRNA Biology

Nature interviews Guttman Lab in this week’s Technology Feature discussing the latest technological advances for studying 3D genome organization. In concert with the in situ microscopy renderings created at Caltech’s Cai Lab, Guttman Lab’s SPRITE method has opened the door to discovery driven proximity interactions – even long distance interactions.

Guttmanlab.caltech.edu

DA: 22 PA: 22 MOZ Rank: 25

RNA-RNA Interactions Enable Specific Targeting of …

Intermolecular RNA-RNA interactions are used by many noncoding RNAs (ncRNAs) to achieve their diverse functions. To aid in identifying these contacts, we developed a method based on RNA Antisense Purification to systematically map RNA-RNA interactions (RAP-RNA) and applied it to investigate two ncRNAs implicated in RNA processing: U1 snRNA, a …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 48

Editor - Benchling

Cut sites of enzymes that you select are highlighted to help guide your work. (Enzymes with compatible ends turn the same color.) Selecting cut sites and copying the sequence will also activate enzymes.

Benchling.com

DA: 13 PA: 16 MOZ Rank: 33

Brian J Haas & Michael C Zody - lncrna-test.caltech.edu

422 volume 28 number 5 mAY 2010 nature biotechnology the Trapnell et al.4 data, indicating that these are highly expressed genes that were easily identified from clone-based cDNA sequenc-ing (Guttman et al.5 do not provide an identi- …

Lncrna-test.caltech.edu

DA: 27 PA: 20 MOZ Rank: 52

caltech – lncRNA Blog

Post-doc positions available – The Guttman Lab for lncRNA Biology February 27, 2017 Leave a comment 3,007 Views Positions We are seeking highly motivated individuals with a passion for understanding the role of large non-coding RNAs in genome regulation and cell fate decisions.

Lncrnablog.com

DA: 18 PA: 13 MOZ Rank: 37

Mitchell Guttman | Biology and Biological Engineering

Computation and Neural Systems (CNS) Open Computation and Neural Systems (CNS) Submenu

Bbe.caltech.edu

DA: 19 PA: 24 MOZ Rank: 50

Water Flea Boasts Whopper Gene Count - lncrna-test.caltech.edu

Protein-coding genes have long been the stars of the Human Genome Project, but now RNA is moving into the limelight. Over the past 3 years, researchers have come to realize that

Lncrna-test.caltech.edu

DA: 27 PA: 21 MOZ Rank: 56

Re-evaluating the foundations of lncRNA–Polycomb function

Many lncRNAs are thought to interact with the polycomb repressive complex 2 (PRC2) in order to regulate gene expression. A central example of this lncRNA–PRC2 paradigm in gene regulation is HOTAIR. In this issue of The EMBO Journal, a study (Portoso et al, 2017) reports that while HOTAIR binds PRC2 with high affinity, the complex itself is dispensable for HOTAIR‐mediated …

Authors.library.caltech.edu

DA: 27 PA: 7 MOZ Rank: 43

The Xist lncRNA exploits three-dimensional genome architecture …

RNA Antisense Purification accurately purifies lncRNA-chromatin interactions (A) Schematic diagram of RAP. Biotinylated probes (blue) are hybridized to the target RNA (red) crosslinked to proteins and DNA. Gray inset: 120-mer antisense capture probes are designed to tile across the entire target RNA. (B) RT-qPCR of the RNA captured using antisense probes to …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 55

The Xist lncRNA Exploits Three-Dimensional Genome Architecture …

These findings suggest a model in which Xist coats the X chromosome by searching in three dimensions, modifying chromosome structure, and spreading to newly accessible locations. Mammalian genomes encode thousands of large noncoding RNAs (lncRNAs) ( 1 – 5 ), many of which play key functional roles in the cell ( 6 – 9 ).

Science.org

DA: 15 PA: 28 MOZ Rank: 54

Phase separation drives X-chromosome inactivation: a hypothesis

6 Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. [email protected]. 7 Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. [email protected].

Pubmed.ncbi.nlm.nih.gov

DA: 23 PA: 10 MOZ Rank: 45

Cell scientist to watch – Mitchell Guttman

Functionallargenon-codingRNA(lncRNA)genes,hislaboratoryaims to understand the mechanisms by which lncRNAs act to control cellular functions through regulation of proteins, binding to genomic DNA targets and contributing to nuclear organisation. What inspired you to become a scientist? I always enjoyed science and when I was a sophomore [age 15 or

Authors.library.caltech.edu

DA: 27 PA: 22 MOZ Rank: 62

Hushing the X Chromosome | www.caltech.edu

Whitney Clavin. (626) 395‑1944. [email protected]. The X chromosome (pink) is seen attached to the nuclear envelope (green) in the image on the right, showing a cellular nucleus through a microscope; the image on the left shows the X chromosome before it moves over. This is a key step in the process of X chromosome silencing.

Caltech.edu

DA: 15 PA: 38 MOZ Rank: 67

Caltech, JPL Team Up to Take On Big-Data Projects

The Caltech center is also interested in this kind of methodology transfer—the application of data tools and techniques developed for one field to another. The CD 3 recently collaborated on one such project with Ralph Adolphs, Bren Professor of Psychology and Neuroscience and professor of biology at Caltech. They used tools based on machine ...

Caltech.edu

DA: 15 PA: 50 MOZ Rank: 87

The Xist lncRNA interacts directly with SHARP to silence ... - Nature

Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, 91125, California, USA Annie Moradian, Michael J. …

Nature.com

DA: 14 PA: 22 MOZ Rank: 52

‪John Rinn‬ - ‪Google Scholar‬

Mitchell Guttman Professor of Biology, California Institute of Technology Verified email at lncrna.caltech.edu Manuel Garber University of Massachusetts Medical School Verified email at umassmed.edu David R Kelley Calico Labs Verified email at calicolabs.com

Scholar.google.com

DA: 18 PA: 10 MOZ Rank: 45

Caltech, JPL Team Up to Take On Big-Data Projects

The Caltech center is also interested in this kind of methodology transfer—the application of data tools and techniques developed for one field to another. The CD 3 recently collaborated on one such project with Ralph Adolphs, Bren Professor of Psychology and Neuroscience and professor of biology at Caltech. They used tools based on machine ...

Cce.caltech.edu

DA: 15 PA: 50 MOZ Rank: 100

A human ESC-based screen identifies a role for the translated …

To generate clonal lncRNA knockout hESC lines, combinations of pSpCas9(BB)−2A-Puro plasmid pairs (Addgene plasmid #62988, RRID:Addgene_62988, gift from Feng Zhang) expressing Cas9 and single sgRNAs targeting upstream and downstream regions of the lncRNA promoter/locus were co-transfected into 1.5 × 10 6 H1 hESCs using the Human Stem Cell …

Ncbi.nlm.nih.gov

DA: 20 PA: 25 MOZ Rank: 64

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