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N/Athe homepage of the gsk global corporate website.
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N/Afind more information about gsk products and therapeutic areas impacted by the gsk portfolio of brands. also, find links to educational resources for you and your patients.
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N/Alearn about gsk health partner, which develops and markets consumer preferred and expert recommended brands in oral health, pain relief and more.
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- Domain created: 2016-10-19T16:13:28Z
- Domain updated: 2025-09-19T05:33:13Z
- Domain expires: 2026-10-19T16:13:28Z 0 Years, 344 Days left
- Website age: 9 Years, 20 Days
- Registrar Domain ID: 2067332033_DOMAIN_COM-VRSN
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- Registrar Abuse Contact Email: [email protected]
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Network
- inetnum : 108.59.80.0 - 108.59.95.255
- name : GOOGLE-CLOUD
- handle : NET-108-59-80-0-1
- status : Direct Allocation
- created : 2006-09-29
- changed : 2019-11-01
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| IP address | 108.59.83.162 |
| Location | Mountain View United States |
| Latitude | 37.4043 |
| Longitude | -122.0748 |
| Metro Code | 807 |
| Timezone | America/Los_Angeles |
| Postal | 94043 |
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GSK-J1 | Histone Demethylase Inhibitor | MedChemExpress
GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. GSK-J1 is selective for H3K27 demethylases of the KDM6 subfamily and specifically binds to endogenous JMJD3. GSK-J1 inhibits TNF-α production by human primary macrophages in an H3K27-dependent manner [1].
Medchemexpress.comDA: 22 PA: 12 MOZ Rank: 34
GSK J1 Supplier | CAS 1373422-53-7 | GSKJ1 | Tocris …
Biological Activity for GSK J1. GSK J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 (KDM6B) and UTX (KDM6A) (IC 50 values are 28 and 53 nM respectively). Also …
Tocris.comDA: 14 PA: 21 MOZ Rank: 36
GSK J1 |GSK-J1 | Histone demethylase inhibitor | Hello Bio
GSK J1. Description. Potent, selective histone demethylase KDM6 subfamily inhibitor. Alternative names. GSK-J1. Purity. >99%. Biological Data Solubility & Handling Chemical Data Related …
Hellobio.comDA: 12 PA: 12 MOZ Rank: 26
GSK J1 (CAS 1373422-53-7): R&D Systems
GSK J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 (KDM6B) and UTX (KDM6A) (IC 50 values are 28 and 53 nM respectively). Also inhibits KDM5B, KDM5C and …
Rndsystems.comDA: 18 PA: 21 MOZ Rank: 42
GSK-J1 | Xpress Biotech International
GSK-J1 $ 138.00. GSK-J1 quantity. Add to cart. Sales on this site ship only to the US and Canada. For other international orders, please email us at [email protected]. SKU: …
Xpressbio.comDA: 13 PA: 16 MOZ Rank: 33
GSK-J1, H3K27 histone demethylase inhibitor (ab144396)
2D chemical structure image of ab144396, GSK-J1, H3K27 histone demethylase inhibitor. Protocols. To our knowledge, customised protocols are not required for this product. Please try …
Abcam.comDA: 13 PA: 50 MOZ Rank: 75
(SYN-3030) GSK-J1 - SYNkinase - CiteAb
(SYN-3030) GSK-J1 Biochemical info; Supplier SYNkinase. PubChem CID 56963315. Molecular Weight 389.4 Inchi Key AVZCPICCWKMZDT-UHFFFAOYSA-N IUPAC Name 3-[[2-pyridin-2 …
Citeab.comDA: 14 PA: 38 MOZ Rank: 58
GSK J1 – biobender.com
As GSK J1 in the last research with (Suzuki et al. 1997 revealed clustered centromeres during pre-meiotic interphase also. After entry in to the leptotene stage these centromeric …
Biobender.comDA: 13 PA: 12 MOZ Rank: 32
GSK J1 | H3K27 demethylase JMJD3 inhibitor | Cas# 1373422-53-7
Background. GSK J1 is a potent and selective inhibitor of the histone H3 lysine 27 (H3K27) demethylase JMJD3, a Fe2+- and α-ketoglutarate-dependent oxygenase involved in a variety …
Glpbio.comDA: 14 PA: 12 MOZ Rank: 34
Inhibition of demethylases by GSK-J1/J4 | Nature
The highly polar GSK-J1 compound is restricted from entering into cells, and Kruidenier et al. 1 therefore changed the acid group in GSK-J1 and GSK-J2 to an ester, …
Nature.comDA: 14 PA: 21 MOZ Rank: 44
GSK J1 | ≥99%(HPLC) | Histone demethylase inhibitor | AdooQ®
GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX . Targets. JMJD3 (KDM6B) UTX (KDM6A) 28 nM: 53 nM: Solubility * In vitro: DMSO 70 mg/mL …
Adooq.comDA: 13 PA: 12 MOZ Rank: 35
GSK-J1 (lithium salt) | C22H22LiN5O2 - PubChem
GSK-J1 (lithium salt) | C22H22LiN5O2 | CID 78357797 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...
Pubchem.ncbi.nlm.nih.govDA: 24 PA: 30 MOZ Rank: 65
Therapeutically targeting head and neck squamous cell carcinoma …
Chemical combination screen identifies GSK-J1 acting synergistically with TCP in HNSCC cells. Recently, we and others have offered evidence that LSD1 inhibition by TCP or …
Nature.comDA: 14 PA: 27 MOZ Rank: 53
GSK-J1 = 98 HPLC 1373422-53-7
GSK-J1 is a potent selective jumonji H3K27 demethylase inhibitor. Jumonji C domain-containing histone demethylases (JHDMs) are Fe(II) and α-ketoglutarate dependent enzymes that …
Sigmaaldrich.comDA: 20 PA: 28 MOZ Rank: 61
GSK-J1 a histone demethylase (HDM) inhibitor of H3K27
A potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC 50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific …
Activemotif.comDA: 19 PA: 46 MOZ Rank: 79
GSK J1|1373422-53-7|MOLNOVA
GSK J1 ( GSKJ1; GSKJ 1; GSKJ-1 ) Catalog No. M17982 CAS No. 1373422-53-7 GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free …
Molnova.comDA: 15 PA: 29 MOZ Rank: 59
gsk j1 – IBA – The TAG Company, Cell TAGnology – Cloning – …
Category: gsk j1. Blog / cd14 antibody / cd163 antibody / Gerbil / Goat / gsk j1 / Guinea Pig / Hamster / Helicobacter / Horse / human recombinant insulin / ihc kit / Pure / Purification / …
Iba-biotagnology.comDA: 24 PA: 17 MOZ Rank: 57
GSK-J1 sodium salt | VWR
Learn more about GSK-J1 sodium salt. We enable science by offering product choice, services, process excellence and our people make it happen.
Ca.vwr.comDA: 10 PA: 45 MOZ Rank: 72
GSK J1 | CAS 1373422-53-7 | AbMole BioScience | GSK J1 Price
Therapeutically targeting head and neck squamous cell carcinoma through synergistic inhibition of LSD1 and JMJD3 by TCP and GSK-J1 [2] Eric Murillo-Rodrguez, et al. Sleep and …
Abmole.comDA: 14 PA: 21 MOZ Rank: 53
GSK J1, Tocris Bioscience | Fisher Scientific
Shop a large selection of products and learn more about GSK J1, Tocris Bioscience. 10mg.
Fishersci.comDA: 17 PA: 37 MOZ Rank: 73
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