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2-NBDG | ≥99%(HPLC) | Selleck | Others - Selleckchem.com
In vivo Formulation Calculator (Clear solution) Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment) Dosage: mg/kg Average weight of animals: g Dosing volume per animal: μL Number of animals: Step 2: Enter the in vivo formulation ( This is only the calculator, not formulation.
Selleckchem.comDA: 19 PA: 21 MOZ Rank: 40
file.selleck.cn
S3648 Amlexanox.cdx csChFnd80/12041713202D 22 24 0 0 0 0 0 0 0 0999 V2000 7.2876 2.1158 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2876 0.7052 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 ...
File.selleck.cnDA: 15 PA: 42 MOZ Rank: 58
Dacomitinib (PF-00299804) | EGFR 抑制剂 | 现货供应 - Selleck
Dacomitinib (PF299804, PF299)是一种有效的,不可逆的泛ErbB抑制剂,最有效作用于EGFR,无细胞试验中IC50为6 nM。Dacomitinib 抑制 ERBB2 和 ERBB4 ,其对应的IC50值分别为45.7 nM和73.7 nM。Dacomitinib 可高效作用于携带EGFR或ERBB2突变型(耐Gefitinib)和携带EGFR T790M突变型的NSCLCs。Dacomitinib 可抑制细胞生长并诱导凋亡。
Selleck.cnDA: 14 PA: 23 MOZ Rank: 39
Erdafitinib (JNJ-42756493) | FGFR 抑制剂 - Selleck
生物活性. 产品描述. Erdafitinib (JNJ-42756493)是有效的、具有选择性和口服生物活性的泛 成纤维细胞生长因子受体FGFR 抑制剂,具有潜在的抗肿瘤活性。. Erdafitinib 也能结合 RET (c-RET) 、 CSF-1R 、 PDGFR-α/PDGFR-β 、 FLT4 、 Kit (c-Kit) 和 VEGFR-2 并可诱导细胞凋亡。.
Selleck.cnDA: 14 PA: 39 MOZ Rank: 56
AZD5582 | IAP 抑制剂 | 现货供应 | 美国品牌 | 免费采购电话400 …
体内研究: 在移植了Panc-1细胞的移植瘤模型中,AZD5582给药后,肿瘤生长和重量减少,而剪切(切割)的caspase 3表达上升 。 对MDA-MB-231携瘤小鼠给予3 mg/kg AZD5582静脉注射的处理,AZD5582在肿瘤细胞中导致cIAP1的降解和caspase 3的裂解,两个星期的处理后,肿瘤大量消退。
Selleck.cnDA: 14 PA: 22 MOZ Rank: 40
FB23-2 (5mg) from selleckchem | SmallMolecules.com
FB23-2 supplied by selleckchem at 5mg. Browse all FB23-2 products on SmallMolecules.com.
Smallmolecules.comDA: 18 PA: 45 MOZ Rank: 68
Lenvatinib (E7080) | VEGFR 抑制剂 | 现货供应 | 美国品牌 | 免费采购 …
定制您的化合物库. 通过在我们的库存中挑选化合物来建立合适的化合物库,用于您的研究工作。 您可以选择:
Selleck.cnDA: 14 PA: 20 MOZ Rank: 40
Brigatinib (AP26113) | ALK 抑制剂 | 现货供应 - Selleck
Brigatinib (AP26113) 是一种有效的、选择性的 ALK 抑制剂,IC50=0.6 nM;也是 ROS1 抑制剂,IC50=0.9 nM。. 它还能以相对较低的效力抑制IGF-1R、FLT3、FLT3 (D835Y)和EGFR。. 除了ALK, IGF1R和InsR,brigatinib也能有效地抑制FLT3和ROS1,IC50分别为2.1 nM和1.9 nM。. 在1 μM时,brigatinib对c-Met或Ron ...
Selleck.cnDA: 14 PA: 33 MOZ Rank: 54
Famciclovir (50mg) from selleckchem | SmallMolecules.com
Famciclovir supplied by selleckchem at 50mg. Browse all Famciclovir products on SmallMolecules.com.
Smallmolecules.comDA: 18 PA: 50 MOZ Rank: 76
YM155 (Sepantronium Bromide) | 购买Survivin 抑制剂 - Selleck
YM155 (Sepantronium Bromide)是一种有效的survivin抑制药,通过抑制Survivin启动子活性而发挥作用,在HeLa-SURP-luc 和 CHO-SV40-luc细胞中IC50为0.54 nM;对SV40启动子活性抑制作用不显著,能够轻微抑制Survivin与XIAP相互作用。YM155 在乳腺癌细胞中可下调 survivin 和 XIAP、调节自噬并诱导自噬依赖的DNA损伤。
Selleck.cnDA: 14 PA: 20 MOZ Rank: 43
Known Bioactive Library: Selleck Bioactive 10mM, 3.33mM, 1
ICCB-L Plate (10mM / 3.33mM / 1.11mM) ICCB-L Well Vendor ID Compound Name Max Solubility in DMSO (mM) Pathway Targets Information CAS Number Form URL
Iccb.med.harvard.eduDA: 20 PA: 50 MOZ Rank: 82
FCCP (10mg) from selleckchem | SmallMolecules.com
FCCP supplied by selleckchem at 10mg. Browse all FCCP products on SmallMolecules.com.
Smallmolecules.comDA: 18 PA: 40 MOZ Rank: 69
Famotidine (50mg) from selleckchem | SmallMolecules.com
Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
Smallmolecules.comDA: 18 PA: 48 MOZ Rank: 78
file.selleck.cn
Famotidine.cdx csChFnd80/03141313152D 20 20 0 0 0 0 0 0 0 0999 V2000 0.0000 2.7354 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2167 3.4379 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 2 ...
File.selleck.cnDA: 15 PA: 50 MOZ Rank: 78
Fasiglifam (TAK-875) (5mg) from selleckchem | SmallMolecules.com
Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
Smallmolecules.comDA: 18 PA: 50 MOZ Rank: 88
Compound Sets - NCI DTP Data - NCI Wiki
NSC numbers and PubChem SID - divii_mlsmr.csv structure in SD file format - Div4_2DStructures_Oct2014.sdf Diversity Set III. Plate maps (plates 4720-4739) - Div3_Platemap.csv structure in SD file format - Div3_2DStructures_Oct2014.sdf Mechanistic Set
Wiki.nci.nih.govDA: 16 PA: 33 MOZ Rank: 64
CFTR mRNAs with nonsense codons are degraded by the SMG6 …
See Source Data file for the exact p-values. Source data are provided as a Source Data file. Full size image. We then tested if the upregulation of CFTR nonsense codon-containing mRNAs, which were ...
Nature.comDA: 14 PA: 28 MOZ Rank: 58
Ezh2 competes with p53 to license lncRNA Neat1 transcription for ...
DZNeP (S7120), EED226 (S8496), EX527 (S1541), Nicotinamide Riboside Chloride (S2935), β-Nicotinamide Mononucleotide (S5259) and Nutlin3 (S1061) were from SelleckChem. Thioglycolate broth (211716 ...
Nature.comDA: 14 PA: 28 MOZ Rank: 59
Flavoxate HCl (10mM/1mL) from selleckchem | SmallMolecules.com
Flavoxate HCl supplied by selleckchem at 10mM/1mL. Browse all Flavoxate HCl products on SmallMolecules.com.
Smallmolecules.comDA: 18 PA: 50 MOZ Rank: 89
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